Why is amlodipine given at night?


What are the precautions of amlodipine?

Use extra care during exercise or hot weather . Check with your doctor right away if you or your child have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem.

What are complications of amlodipine?

The more common side effects that can occur with amlodipine include:
  • swelling of your legs or ankles.
  • tiredness or extreme sleepiness.
  • stomach pain.
  • nausea.
  • dizziness.
  • hot or warm feeling in your face (flushing)
  • irregular heart rate (arrhythmia)
  • very fast heart rate (palpitations)

What drugs interact with amlodipine besylate?

Amlodipine can potentially interact with some other medications, including:
  • Simvastatin. The FDA recommends limiting the dosage of simvastatin to 20mg daily while also taking amlodipine.
  • CYP3A4 inhibitors. …
  • Cyclosporine.

What should you assess before giving amlodipine?

Examination and Evaluation
  1. Assess heart rate, ECG, and heart sounds, especially during exercise (See Appendices G, H). …
  2. Assess blood pressure periodically, and compare to normal values (see Appendix F) to help document antihypertensive effects.
  3. Assess episodes of angina pectoris at rest and during exercise.

Why is amlodipine given at night?

It does not matter what time of day you take amlodipine (morning or evening) but it is best to take it at the same time every day, when you are most likely to remember, for more even blood levels and therefore effectiveness . Amlodipine is a calcium channel blocker that dilates blood vessels and improves blood flow.
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When should I stop taking amlodipine?

How long to take it for. Usually, treatment with amlodipine is long term, even for the rest of your life. Talk to your doctor if you want to stop taking amlodipine . Stopping may cause your blood pressure to rise, and this may increase your risk of heart attack and stroke.

What does amlodipine do to the heart?

Amlodipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. This relaxes the blood vessels and lowers blood pressure, and increases the supply of blood and oxygen to the heart while reducing its workload .

How much does 5mg amlodipine lower BP?

Titration of amlodipine from 5 to 10 mg daily in patients not responding to treatment with the 5 mg dose resulted in a statistically significant decrease in blood pressure: systolic blood pressure by −12.4 mm Hg (SE = 0.53) and diastolic blood pressure by −7.2 mm Hg (SE = 0.32) (both P < 0.0001; Figure ​ 3).

Does amlodipine affect heart rate?

Myth #4: Amlodipine lowers your heart rate

Nope, not true. Unlike beta blockers and other calcium channel blockers (like diltiazem and verapamil), amlodipine usually has little to no effect on your heart rate . Amlodipine primarily lowers blood pressure — either alone or in combination with other medications.

Can you take vitamin D with amlodipine?

Interactions between your drugs

No interactions were found between amlodipine and Vitamin D3 .

What should you not take with blood pressure medicine?

Topic Overview
  • Decongestants, such as those that contain pseudoephedrine.
  • Pain medicines (NSAIDs), such as ibuprofen and naproxen.
  • Cold and influenza medicines. These often contain decongestants and NSAIDs.
  • Some antacids and other stomach medicines. …
  • Some natural health products.
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What is the safest high blood pressure medication?

Methyldopa, which works to lower blood pressure through the central nervous system, has the lowest risk of harming the mother and developing fetus. Other possible safe options include labetalol, beta-blockers, and diuretics .

How quickly does amlodipine lower BP?

Although each dose of amlodipine begins working as soon as it enters the blood, it takes 6-12 hours for amlodipine to reach its greatest effect. This means your blood pressure should begin to go down within 12 hours of taking amlodipine.

Does amlodipine lower systolic or diastolic?

Amlodipine 10 mg lowered systolic blood pressure by −13.3 mm Hg (95% CI: −15.5 to −11.0) and diastolic blood pressure by −9.2 mm Hg (95% CI: −10.6 to −7.8) at the final visit (P < 0.0001 for both).

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